ETA-receptor blockade and ETB-receptor stimulation in experimental congenital diaphragmatic hernia BERNARD THÉBAUD,1,2 PASCAL DE LAGAUSIE,1,3 DOMINIQUE FORGUES,4 YVES AIGRAIN,3,5 JEAN-CHRISTOPHE MERCIER,6 AND A. TUAN DINH-XUAN1

نویسندگان

  • BERNARD THÉBAUD
  • PASCAL DE LAGAUSIE
  • DOMINIQUE FORGUES
  • JEAN - CHRISTOPHE MERCIER
  • A. TUAN DINH - XUAN
چکیده

BERNARD THÉBAUD,1,2 PASCAL DE LAGAUSIE,1,3 DOMINIQUE FORGUES,4 YVES AIGRAIN,3,5 JEAN-CHRISTOPHE MERCIER,6 AND A. TUAN DINH-XUAN1 2Service de Réanimation Néonatale, Hôpital Antoine Béclère, Université Paris-Sud, 92140 Clamart; 1Service de Physiologie-Explorations Fonctionnelles, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris-Université Paris V, 75014 Paris; 3Service de Chirurgie Viscérale Pédiatrique and 6Service de Réanimation Pédiatrique, Hôpital Robert Debré, Assistance Publique-Hôpitaux de Paris-Université Paris VII, 75019 Paris; 5Ecole de Chirurgie, Assistance Publique-Hôpitaux de Paris, 75005 Paris; and 5Service de Chirurgie Viscérale Infantile, Centre Hospitalier Universitaire Montpellier, 34000 Montpellier, France

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

ALUNG August 21/2

BERNARD THÉBAUD,1,2 DICK TIBBOEL,3 CAROLINE RAMBAUD,4 JEAN-CHRISTOPHE MERCIER,5 JACQUES R. BOURBON,6 A. TUAN DINH-XUAN,2 AND STEPHEN L. ARCHER7 1Réanimation Néonatale and 4Service d’Anatomo-Pathologie, Hôpital Antoine Béclère, 92141 Clamart; 2Service de Physiologie, Hôpital Cochin, Université René Descartes, 75679 Paris Cedex 14; 5Réanimation Pédiatrique, Hôpital Robert Debré, 75019 Paris; 6Ins...

متن کامل

Vitamin A decreases the incidence and severity of nitrofen-induced congenital diaphragmatic hernia in rats.

Congenital diaphragmatic hernia (CDH) is a major cause of refractory respiratory failure in the newborn. Pulmonary hypoplasia often limits survival. Vitamin A (Vit A) is an important signal for lung growth. We hypothesized that antenatal treatment with Vit A would stimulate lung growth and decrease mortality in experimental CDH induced in rats by ingestion of the herbicide nitrofen (2,4-dichlor...

متن کامل

Pulmonary clearance of circulating endothelin-1 in dogs in vivo: exclusive role of ETB receptors.

The pulmonary circulation plays an important role in the removal of circulating endothelin-1 (ET-1). Plasma ET-1 levels are increased in pulmonary hypertensive states of various etiologies (e.g., idiopathic, heart failure, and congenital anomalies) in proportion to the severity of pulmonary hypertension. It is possible that reduced pulmonary clearance of this peptide contributes to the hyperend...

متن کامل

Significance of the endothelin ETA receptor in the haemodynamic and inotropic effects of endothelin-1 in rats.

The main aim of the present study was to investigate the direct inotropic effects of stimulation of the endothelin (ET) receptor ETA under in vivo conditions. It is well known that ETA receptor stimulation causes pronounced vasoconstriction. The ET-1-induced coronary vasoconstriction may lead to myocardial ischaemia and, consequently, to cardiodepressor effects that may mask the direct positive...

متن کامل

Cerebrospinal Fluid from Patients with Subarachnoid Haemorrhage and Vasospasm Enhances Endothelin Contraction in Rat Cerebral Arteries

INTRODUCTION Previous studies have suggested that cerebrospinal fluid from patients with subarachnoid hemorrhage (SAH) leads to pronounced vasoconstriction in isolated arteries. We hypothesized that only cerebrospinal fluid from SAH patients with vasospasm would produce an enhanced contractile response to endothelin-1 in rat cerebral arteries, involving both endothelin ETA and ETB receptors. ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2000